This book systematically presents Siemens S7-1200 PLC applications through a four-phase framework (fundamentals, simulation, programming, development). Featuring industry-education co-developed content with TIA Portal virtual platforms and real-world cases, it employs a six-step pedagogical model integrating goal orientation, knowledge mapping, and hands-on practice. The competency-based approach combines hardware configuration, debugging techniques, and visual diagnostic tools to bridge smart manufacturing skill requirements, establishing a closed-loop technical education system for industrial automation.